Ethacrynic acid D5
Modify Date: 2024-01-07 13:14:33
Ethacrynic acid D5 structure
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Common Name | Ethacrynic acid D5 | ||
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| CAS Number | 1330052-59-9 | Molecular Weight | 308.169 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 480.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C13H7D5Cl2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 244.1±28.7 °C | |
Use of Ethacrynic acid D5Ethacrynic acid D5 is a deuterium labeled Ethacrynic acid. Ethacrynic acid is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4]. |
| Name | {2,3-Dichloro-4-[2-methylene(2H5)butanoyl]phenoxy}acetic acid |
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| Synonym | More Synonyms |
| Description | Ethacrynic acid D5 is a deuterium labeled Ethacrynic acid. Ethacrynic acid is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4]. |
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| Related Catalog | |
| Target |
Glutathione S-transferases (GSTs)[1]; NF-κB-signaling pathway[2]; L-type voltage-dependent and store-operated calcium channel[3] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 480.0±45.0 °C at 760 mmHg |
| Molecular Formula | C13H7D5Cl2O4 |
| Molecular Weight | 308.169 |
| Flash Point | 244.1±28.7 °C |
| Exact Mass | 307.042633 |
| LogP | 3.36 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.559 |
| Hazard Codes | Xi |
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| {2,3-Dichloro-4-[2-methylene(2H5)butanoyl]phenoxy}acetic acid |
| Acetic acid, 2-[2,3-dichloro-4-(2-methylene-1-oxobutyl-3,3,4,4,4-d5)phenoxy]- |