Diazo Biotin-PEG3-azide

Modify Date: 2024-01-12 21:58:36

Diazo Biotin-PEG3-azide Structure
Diazo Biotin-PEG3-azide structure
Common Name Diazo Biotin-PEG3-azide
CAS Number 1339202-33-3 Molecular Weight 711.831
Density N/A Boiling Point N/A
Molecular Formula C33H45N9O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diazo Biotin-PEG3-azide


Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diazo Biotin-PEG3-Azide
Synonym More Synonyms

 Diazo Biotin-PEG3-azide Biological Activity

Description Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C33H45N9O7S
Molecular Weight 711.831
Exact Mass 711.316284
LogP 1.07

 Synonyms

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[13-[4-[(E)-2-[5-(2-azidoethyl)-2-hydroxyphenyl]diazenyl]phenyl]-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-
Diazo biotin-azide
4-{(E)-[5-(2-Azidoethyl)-2-hydroxyphenyl]diazenyl}-N-{13-oxo-17-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-3,6,9-trioxa-12-azaheptadec-1-yl}benzamide
MFCD28334530
Azo biotin-azide
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