IDH-C227

Modify Date: 2024-01-11 19:37:40

IDH-C227 Structure
IDH-C227 structure
Common Name IDH-C227
CAS Number 1355324-14-9 Molecular Weight 498.59100
Density N/A Boiling Point N/A
Molecular Formula C30H31FN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IDH-C227


IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].

 Names

Name 2-((4-cyanophenyl)amino)-N-(2-(cyclohexylamino)-2-oxo-1-(o-tolyl)ethyl)-N-(3-fluorophenyl)acetamide

 IDH-C227 Biological Activity

Description IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].
Related Catalog
In Vitro IDH-C227 shows anticancer effcts, with IC50 values of <0.1 μM and 0.25 μM against HT1080 and U87MG cells, respectively[1].
References

[1]. Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel). 2018 Feb 11;10(2):49.

 Chemical & Physical Properties

Molecular Formula C30H31FN4O2
Molecular Weight 498.59100
Exact Mass 498.24300
PSA 85.23000
LogP 6.10498