Biotin-PEG2-acid

Modify Date: 2024-01-02 20:35:07

Biotin-PEG2-acid Structure
Biotin-PEG2-acid structure
Common Name Biotin-PEG2-acid
CAS Number 1365655-89-5 Molecular Weight 403.494
Density 1.2±0.1 g/cm3 Boiling Point 752.2±60.0 °C at 760 mmHg
Molecular Formula C17H29N3O6S Melting Point N/A
MSDS N/A Flash Point 408.7±32.9 °C

 Use of Biotin-PEG2-acid


Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 3-{2-[2-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}propanoic acid
Synonym More Synonyms

 Biotin-PEG2-acid Biological Activity

Description Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro Biotin-PEG2-acid is used to cap the N-terminus of the peptide while the peptide was still attached to the resin[1].
References

[1]. Merg AD, et al. Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures. J Am Chem Soc. 2019 Dec 26;141(51):20107-20117.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 752.2±60.0 °C at 760 mmHg
Molecular Formula C17H29N3O6S
Molecular Weight 403.494
Flash Point 408.7±32.9 °C
Exact Mass 403.177704
LogP -1.05
Vapour Pressure 0.0±5.4 mmHg at 25°C
Index of Refraction 1.527
Storage condition -20°C

 Synonyms

Propanoic acid, 3-[2-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]-
3-{2-[2-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}propanoic acid
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