Biotin-PEG2-C2-iodoacetamide

Modify Date: 2024-01-09 12:06:36

Biotin-PEG2-C2-iodoacetamide Structure
Biotin-PEG2-C2-iodoacetamide structure
Common Name Biotin-PEG2-C2-iodoacetamide
CAS Number 292843-75-5 Molecular Weight 542.43
Density N/A Boiling Point N/A
Molecular Formula C18H31IN4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG2-C2-iodoacetamide


Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG2-C2-iodoacetamide

 Biotin-PEG2-C2-iodoacetamide Biological Activity

Description Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H31IN4O5S
Molecular Weight 542.43