Biotin-PEG2-Mal

Modify Date: 2024-01-04 21:36:49

Biotin-PEG2-Mal Structure
Biotin-PEG2-Mal structure
Common Name Biotin-PEG2-Mal
CAS Number 305372-39-8 Molecular Weight 525.618
Density 1.3±0.1 g/cm3 Boiling Point 897.0±65.0 °C at 760 mmHg
Molecular Formula C23H35N5O7S Melting Point N/A
MSDS N/A Flash Point 496.3±34.3 °C

 Use of Biotin-PEG2-Mal


Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

 Names

Name N-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
Synonym More Synonyms

 Biotin-PEG2-Mal Biological Activity

Description Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 897.0±65.0 °C at 760 mmHg
Molecular Formula C23H35N5O7S
Molecular Weight 525.618
Flash Point 496.3±34.3 °C
Exact Mass 525.225708
PSA 190.94000
LogP -1.76
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.550
Storage condition -20 ℃

 Safety Information

Hazard Codes Xi

 Synonyms

N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
B3174
N-{2-[2-(2-{[3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]amino}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
Maleimide-PEG2-Biotin
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