LDHA-IN-4

Modify Date: 2024-02-05 14:37:43

LDHA-IN-4 Structure
LDHA-IN-4 structure
Common Name LDHA-IN-4
CAS Number 1370290-34-8 Molecular Weight 497.563
Density 1.4±0.1 g/cm3 Boiling Point 843.9±65.0 °C at 760 mmHg
Molecular Formula C25H27N3O6S Melting Point N/A
MSDS N/A Flash Point 464.2±34.3 °C

 Use of LDHA-IN-4


AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM[1].

 Names

Name {4-[4-({3-[(2-Methyl-1,3-benzothiazol-6-yl)amino]-3-oxopropyl}amino)-4-oxobutyl]benzyl}malonic acid
Synonym More Synonyms

 LDHA-IN-4 Biological Activity

Description AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM[1].
Related Catalog
References

[1]. Ward RA,et al. Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 843.9±65.0 °C at 760 mmHg
Molecular Formula C25H27N3O6S
Molecular Weight 497.563
Flash Point 464.2±34.3 °C
Exact Mass 497.162048
LogP 2.30
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.659

 Synonyms

Propanedioic acid, 2-[[4-[4-[[3-[(2-methyl-6-benzothiazolyl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]-
{4-[4-({3-[(2-Methyl-1,3-benzothiazol-6-yl)amino]-3-oxopropyl}amino)-4-oxobutyl]benzyl}malonic acid
AZ-33
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