N-dodecanoyl-L-Homoserine lactone

Modify Date: 2024-01-09 14:53:26

N-dodecanoyl-L-Homoserine lactone Structure
N-dodecanoyl-L-Homoserine lactone structure
 Common Name N-dodecanoyl-L-Homoserine lactone
CAS Number 137173-46-7 Molecular Weight 283.40600
Density 1.005g/cm3 Boiling Point 485.84ºC at 760 mmHg
Molecular Formula C16H29NO3 Melting Point N/A
MSDS N/A Flash Point 247.627ºC

 Use of N-dodecanoyl-L-Homoserine lactone


N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1].

 Names

Name N-dodecanoyl-L-Homoserine lactone
Synonym More Synonyms

 N-dodecanoyl-L-Homoserine lactone Biological Activity

Description N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1].
Related Catalog
In Vitro Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance[1].
References

[1]. Borges A, et al. Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes. Biofouling. 2017 Feb;33(2):156-168.

 Chemical & Physical Properties

Density 1.005g/cm3
Boiling Point 485.84ºC at 760 mmHg
Molecular Formula C16H29NO3
Molecular Weight 283.40600
Flash Point 247.627ºC
Exact Mass 283.21500
PSA 55.40000
LogP 3.72990
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.477

 Synonyms

N-dodecanoyl-HSL
N-dodecanoyl-DL-homoserine
3-dodecanoylamino-dihydro-furan-2-one
n-lauroyl-dl-homoserine lactone
N-Dodecanoyl-L-homoserine lactone
N-dodecanoyl-homoserine lactone
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