Azido-PEG1-C2-acid

Modify Date: 2024-01-14 14:33:08

Azido-PEG1-C2-acid Structure
Azido-PEG1-C2-acid structure
Common Name Azido-PEG1-C2-acid
CAS Number 1393330-34-1 Molecular Weight 159.143
Density N/A Boiling Point N/A
Molecular Formula C5H9N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG1-C2-acid


Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG1-acid
Synonym More Synonyms

 Azido-PEG1-C2-acid Biological Activity

Description Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C5H9N3O3
Molecular Weight 159.143
Exact Mass 159.064392
LogP 0.01

 Synonyms

MFCD22574801
Propanoic acid, 3-(2-azidoethoxy)-
3-(2-Azidoethoxy)propanoic acid
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