UNC-1079

Modify Date: 2024-01-07 12:05:56

UNC-1079 Structure
UNC-1079 structure
Common Name UNC-1079
CAS Number 1418741-86-2 Molecular Weight 466.659
Density 1.2±0.1 g/cm3 Boiling Point 640.0±55.0 °C at 760 mmHg
Molecular Formula C28H42N4O2 Melting Point N/A
MSDS N/A Flash Point 264.2±23.9 °C

 Use of UNC-1079


UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 μM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.

 Names

Name 1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)
Synonym More Synonyms

 UNC-1079 Biological Activity

Description UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 μM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.
Related Catalog
References

[1]. James LI, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 640.0±55.0 °C at 760 mmHg
Molecular Formula C28H42N4O2
Molecular Weight 466.659
Flash Point 264.2±23.9 °C
Exact Mass 466.330780
LogP 2.28
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.590
Storage condition 2-8℃

 Synonyms

Methanone, 1,1'-(1,4-phenylene)bis[1-[1,4'-bipiperidin]-1'-yl-
1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)
UNC-1079
UNC1079
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