Ampicillin-d5

Modify Date: 2024-01-02 14:28:22

Ampicillin-d5 Structure
Ampicillin-d5 structure
Common Name Ampicillin-d5
CAS Number 1426173-65-0 Molecular Weight 354.436
Density 1.5±0.1 g/cm3 Boiling Point 683.9±55.0 °C at 760 mmHg
Molecular Formula C16H14D5N3O4S Melting Point N/A
MSDS N/A Flash Point 367.4±31.5 °C

 Use of Ampicillin-d5


Ampicillin-d5 (D-(-)-α-Aminobenzylpenicillin-d5) is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].

 Names

Name Ampicillin-d5
Synonym More Synonyms

 Ampicillin-d5 Biological Activity

Description Ampicillin-d5 (D-(-)-α-Aminobenzylpenicillin-d5) is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Chopra SL, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep;27(9):223-7.

[3]. Lund B, et al. Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin andpivampicillin. Eur J Clin Pharmacol. 1974;7(2):133-5.

[4]. Lee KE, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20(2):185-92.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 683.9±55.0 °C at 760 mmHg
Molecular Formula C16H14D5N3O4S
Molecular Weight 354.436
Flash Point 367.4±31.5 °C
Exact Mass 354.141022
LogP 1.35
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.675

 Synonyms

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-(phenyl-d5)acetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
(2S,5R,6R)-6-{[(2R)-2-Amino-2-(2H5)phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
MFCD19704897
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Ampicillin-d5 suppliers

Ampicillin-d5 price