TC KHNS 11
Modify Date: 2024-01-12 18:50:40
TC KHNS 11 structure
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Common Name | TC KHNS 11 | ||
|---|---|---|---|---|
| CAS Number | 1431540-99-6 | Molecular Weight | 492.53 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 760.5±60.0 °C at 760 mmHg | |
| Molecular Formula | C28H24N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 413.7±32.9 °C | |
Use of TC KHNS 11PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties[1]. |
| Name | 5-(4-{3-[(4-Acetyl-1-piperazinyl)carbonyl]phenyl}-6-quinazolinyl)-2-methoxynicotinonitrile |
|---|---|
| Synonym | More Synonyms |
| Description | PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties[1]. |
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| Related Catalog | |
| Target |
9 nM, 0.262 μM, 1.65 μM, 4.63 μM (PI3Kδ, PI3Kα, PI3Kβ, PI3Kγ)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 760.5±60.0 °C at 760 mmHg |
| Molecular Formula | C28H24N6O3 |
| Molecular Weight | 492.53 |
| Flash Point | 413.7±32.9 °C |
| Exact Mass | 492.190979 |
| LogP | 1.88 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.700 |
| MFCD31689242 |
| 3-Pyridinecarbonitrile, 5-[4-[3-[(4-acetyl-1-piperazinyl)carbonyl]phenyl]-6-quinazolinyl]-2-methoxy- |
| 5-{4-[3-(4-Acetylpiperazine-1-Carbonyl)phenyl]quinazolin-6-Yl}-2-Methoxypyridine-3-Carbonitrile |
| 5-(4-{3-[(4-Acetyl-1-piperazinyl)carbonyl]phenyl}-6-quinazolinyl)-2-methoxynicotinonitrile |