PLB-1001
Modify Date: 2024-01-13 23:04:32
PLB-1001 structure
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Common Name | PLB-1001 | ||
|---|---|---|---|---|
| CAS Number | 1440964-89-5 | Molecular Weight | 424.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H15F3N8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PLB-1001Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1]. |
| Name | Bozitinib |
|---|
| Description | Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Bozitinib (PLB-1001) (30 μM; 6 hours) inhibits the phosphorylation of MET and STAT3, has a robust inhibitory effect of PLB-1001 on MET and its downstream signaling pathways. Western Blot Analysis[1] Cell Line: Human astrocytes (HA) cells Concentration: 30 μM Incubation Time: 6 hours Result: Decreased p-STAT3,p-MET expression. |
| References |
| Molecular Formula | C20H15F3N8 |
|---|---|
| Molecular Weight | 424.38 |
| Storage condition | -20°C |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PLB-1001
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: PLB-1001
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: PLB-1001
- Price: $800.0/100mg $1400.0/250mg $2900.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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