DPM-1001

Modify Date: 2024-01-07 08:53:52

DPM-1001 Structure
DPM-1001 structure
Common Name DPM-1001
CAS Number 1471172-27-6 Molecular Weight 567.85
Density N/A Boiling Point N/A
Molecular Formula C35H57N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DPM-1001


DPM-1001 is a potent, specific, orally bioavailable and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM, an an analog of the specific PTP1B inhibitor trodusquemine (MSI-1436; IC50=600 nM). DPM-1001 has anti-diabetic property[1].

 Names

Name DPM-1001

 DPM-1001 Biological Activity

Description DPM-1001 is a potent, specific, orally bioavailable and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM, an an analog of the specific PTP1B inhibitor trodusquemine (MSI-1436; IC50=600 nM). DPM-1001 has anti-diabetic property[1].
Related Catalog
Target

IC50: 100 nM (PTP1B)[1]

References

[1]. Krishnan N, et al. A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem. 2018 Feb 2;293(5):1517-1525.

 Chemical & Physical Properties

Molecular Formula C35H57N3O3
Molecular Weight 567.85