ROMK-IN-25
Modify Date: 2024-02-06 19:53:08
ROMK-IN-25 structure
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Common Name | ROMK-IN-25 | ||
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| CAS Number | 1443735-02-1 | Molecular Weight | 462.489 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H23FN8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ROMK-IN-25ROMK-IN-25 is a potent and selective ROMK channel (KCNJ1) inhibitor with IC50 of 72 nM; displays improved ROMK/hERG selectivity (866-fold over hERG), and improved pharmacokinetic profiles; does not evoke QTc prolongation in an in vivo cardiovascular dog model. |
| Name | ROMK-IN-25 |
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| Description | ROMK-IN-25 is a potent and selective ROMK channel (KCNJ1) inhibitor with IC50 of 72 nM; displays improved ROMK/hERG selectivity (866-fold over hERG), and improved pharmacokinetic profiles; does not evoke QTc prolongation in an in vivo cardiovascular dog model. |
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| References | References 1. Zhu Y, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5695-5702. View Related Products by Target Potassium Channel |
| Molecular Formula | C23H23FN8O2 |
|---|---|
| Molecular Weight | 462.489 |