Dofetilide N-oxide

Modify Date: 2024-01-19 13:30:37

Dofetilide N-oxide Structure
Dofetilide N-oxide structure
Common Name Dofetilide N-oxide
CAS Number 144449-71-8 Molecular Weight 457.56400
Density N/A Boiling Point N/A
Molecular Formula C19H27N3O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dofetilide N-oxide


Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels[1][2].

 Names

Name Dofetilide N-oxide
Synonym More Synonyms

 Dofetilide N-oxide Biological Activity

Description Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels[1][2].
Related Catalog
Target

Potassium channels[1][2]

References

[1]. Maisch B, et al. Pregnancy and cardiomyopathies. Herz. 2003 May;28(3):196-208.

[2]. Snyders, D.J. and A. Chaudhary, High affinity open channel block by dofetilide of HERG expressed in a human cell line. Mol Pharmacol, 1996. 49(6): p. 949-55.

 Chemical & Physical Properties

Molecular Formula C19H27N3O6S2
Molecular Weight 457.56400
Exact Mass 457.13400
PSA 147.76000
LogP 4.32400

 Synonyms

N-[4-(2-{[2-(4-methanesulfonylamino-phenyl)-ethyl]-methyl-amino}-ethoxy)-phenyl]-methanesulfonamide N-oxide
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