TAT-cyclo-CLLFVY TFA
Modify Date: 2024-01-14 20:25:21
TAT-cyclo-CLLFVY TFA structure
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Common Name | TAT-cyclo-CLLFVY TFA | ||
|---|---|---|---|---|
| CAS Number | 1446322-66-2 | Molecular Weight | 2546.86 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C116H176N32O33 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TAT-cyclo-CLLFVY TFATAT-cyclo-CLLFVY is a selective HIF-1 dimerization inhibitor. TAT-cyclo-CLLFVY blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50=1.3 μM). TAT-cyclo-CLLFVY inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro. TAT-cyclo-CLLFVY also reduces tubularization of hypoxic HUVECs. |
| Name | TAT-cyclo-CLLFVY |
|---|
| Description | TAT-cyclo-CLLFVY is a selective HIF-1 dimerization inhibitor. TAT-cyclo-CLLFVY blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50=1.3 μM). TAT-cyclo-CLLFVY inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro. TAT-cyclo-CLLFVY also reduces tubularization of hypoxic HUVECs. |
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| Related Catalog |
| Molecular Formula | C116H176N32O33 |
|---|---|
| Molecular Weight | 2546.86 |
| Hazard Codes | Xi |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: TAT-cyclo-CLLFVY TFA
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: TAT-cyclo-CLLFVY
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: TAT-cyclo-CLLFVY
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Vinnie
- Email: Jamie@api-made.com
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