Propargyl-PEG9-acid

Modify Date: 2024-01-28 16:54:57

Propargyl-PEG9-acid Structure
Propargyl-PEG9-acid structure
Common Name Propargyl-PEG9-acid
CAS Number 1613752-50-3 Molecular Weight 480.55
Density N/A Boiling Point N/A
Molecular Formula C22H40O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG9-acid


Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG9-acid

 Propargyl-PEG9-acid Biological Activity

Description Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H40O11
Molecular Weight 480.55
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