3'-O-TBDMS-2'-OMe-U

Modify Date: 2024-01-08 22:07:31

3'-O-TBDMS-2'-OMe-U Structure
3'-O-TBDMS-2'-OMe-U structure
Common Name 3'-O-TBDMS-2'-OMe-U
CAS Number 171268-84-1 Molecular Weight 372.49
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C16H28N2O6Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-O-TBDMS-2'-OMe-U


3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

 Names

Name 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-methyluridine
Synonym More Synonyms

 3'-O-TBDMS-2'-OMe-U Biological Activity

Description 3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Related Catalog
References

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C16H28N2O6Si
Molecular Weight 372.49
Exact Mass 372.171661
LogP 1.84
Index of Refraction 1.526
Storage condition 2-8℃

 Synonyms

3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-methyluridine
Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-
3'-O-TBDMS-2'-OMe-U