Azido-PEG3-C-Boc

Modify Date: 2024-01-10 17:46:59

Azido-PEG3-C-Boc Structure
Azido-PEG3-C-Boc structure
Common Name Azido-PEG3-C-Boc
CAS Number 172531-36-1 Molecular Weight 289.32800
Density N/A Boiling Point N/A
Molecular Formula C12H23N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-C-Boc


Azido-PEG3-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name azidotriethylene glycol-Boc
Synonym More Synonyms

 Azido-PEG3-C-Boc Biological Activity

Description Azido-PEG3-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H23N3O5
Molecular Weight 289.32800
Exact Mass 289.16400
PSA 103.74000
LogP 1.14096

 Synonyms

tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate
tert-butyl 2-[2-(2-(2-azidoethoxy)ethoxy)ethoxy]acetate
tert-butyl 11-azido-3,6,9-trioxaundecanoate
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