3’-O-Me-G(iBu)-2’-phosphoramidite

Modify Date: 2024-09-17 16:44:32

3’-O-Me-G(iBu)-2’-phosphoramidite Structure
3’-O-Me-G(iBu)-2’-phosphoramidite structure
Common Name 3’-O-Me-G(iBu)-2’-phosphoramidite
CAS Number 179479-04-0 Molecular Weight 855.91
Density N/A Boiling Point N/A
Molecular Formula C44H54N7O9P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-O-Me-G(iBu)-2’-phosphoramidite


3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name 3’-O-Me-G(iBu)-2’-phosphoramidite

 3’-O-Me-G(iBu)-2’-phosphoramidite Biological Activity

Description 3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Molecular Formula C44H54N7O9P
Molecular Weight 855.91