Azido-PEG5-PFP ester

Modify Date: 2024-01-16 14:23:09

Azido-PEG5-PFP ester Structure
Azido-PEG5-PFP ester structure
Common Name Azido-PEG5-PFP ester
CAS Number 1818294-48-2 Molecular Weight 501.402
Density N/A Boiling Point N/A
Molecular Formula C19H24F5N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-PFP ester


Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG5-PFP ester
Synonym More Synonyms

 Azido-PEG5-PFP ester Biological Activity

Description Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

 Chemical & Physical Properties

Molecular Formula C19H24F5N3O7
Molecular Weight 501.402
Exact Mass 501.153442
LogP 1.31

 Synonyms

MFCD26793782
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-azido-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate
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