Top Suppliers:I want be here


1818294-48-2

1818294-48-2 structure
1818294-48-2 structure
  • Name: Azido-PEG5-PFP ester
  • Chemical Name: Azido-PEG5-PFP ester
  • CAS Number: 1818294-48-2
  • Molecular Formula: C19H24F5N3O7
  • Molecular Weight: 501.402
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-26 06:47:38
  • Modify Date: 2024-01-16 14:23:09
  • Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name Azido-PEG5-PFP ester
Synonyms MFCD26793782
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-azido-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate
Description Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula C19H24F5N3O7
Molecular Weight 501.402
Exact Mass 501.153442
LogP 1.31