2148295-92-3

2148295-92-3 structure
2148295-92-3 structure
  • Name: Propargyl-PEG5-PFP ester
  • Chemical Name: Propargyl-PEG5-PFP ester
  • CAS Number: 2148295-92-3
  • Molecular Formula: C20H23F5O7
  • Molecular Weight: 470.38
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-06-29 10:24:14
  • Modify Date: 2024-01-17 18:07:29
  • Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG5-PFP ester
Synonyms MFCD29049371
Description Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C20H23F5O7
Molecular Weight 470.38