Mal-PEG1-Bromide

Modify Date: 2024-01-10 20:15:59

Mal-PEG1-Bromide Structure
Mal-PEG1-Bromide structure
Common Name Mal-PEG1-Bromide
CAS Number 1823885-81-9 Molecular Weight 248.07
Density N/A Boiling Point N/A
Molecular Formula C8H10BrNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG1-Bromide


Mal-PEG1-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG1-bromide

 Mal-PEG1-Bromide Biological Activity

Description Mal-PEG1-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H10BrNO3
Molecular Weight 248.07
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