NAAA-IN-3

Modify Date: 2024-01-21 09:18:23

NAAA-IN-3 Structure
NAAA-IN-3 structure
Common Name NAAA-IN-3
CAS Number 1831115-59-3 Molecular Weight 264.32
Density N/A Boiling Point N/A
Molecular Formula C17H16N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NAAA-IN-3


NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-3 has the potential for the research of inflammation and pain[1].

 Names

Name NAAA-IN-3

 NAAA-IN-3 Biological Activity

Description NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-3 has the potential for the research of inflammation and pain[1].
Related Catalog
References

[1]. Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195.

 Chemical & Physical Properties

Molecular Formula C17H16N2O
Molecular Weight 264.32