PF-06737007
Modify Date: 2024-07-20 18:19:55
PF-06737007 structure
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Common Name | PF-06737007 | ||
|---|---|---|---|---|
| CAS Number | 1863905-38-7 | Molecular Weight | 528.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H28F4N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-06737007PF-06737007 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 7.7 nM, 15 nM and 3.9 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1]. |
| Name | PF-06737007 |
|---|
| Description | PF-06737007 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 7.7 nM, 15 nM and 3.9 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1]. |
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| Related Catalog | |
| Target |
TrkA:7.7 nM (IC50, in cell-based assays) TrkB:15 nM (IC50, in cell-based assays) TrkC:3.9 nM (IC50, in cell-based assays) |
| In Vitro | PF-06737007 (Compound 13b) exhibits superb Trk selectivity with >95% inhibition of TrkA with no other kinase being inhibited by >40% at 1 μM[1]. |
| References |
| Molecular Formula | C25H28F4N2O6 |
|---|---|
| Molecular Weight | 528.49 |
| Hazard Codes | Xi |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PF-06737007
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: PF-06737007
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: PF-06737007
- Price: $350.0/25mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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