Ac-Trp-Glu-His-Asp-AMC

Modify Date: 2024-01-04 15:44:01

Ac-Trp-Glu-His-Asp-AMC Structure
Ac-Trp-Glu-His-Asp-AMC structure
Common Name Ac-Trp-Glu-His-Asp-AMC
CAS Number 189275-74-9 Molecular Weight 784.771
Density 1.5±0.1 g/cm3 Boiling Point 1399.8±65.0 °C at 760 mmHg
Molecular Formula C38H40N8O11 Melting Point N/A
MSDS N/A Flash Point 800.3±34.3 °C

 Use of Ac-Trp-Glu-His-Asp-AMC


Ac-Trp-Glu-His-Asp-AMC (Ac-Trp-Glu-His-Asp-AMC) is a potent fluorogenic substrate of caspase-1[1].

 Names

Name ac-wehd-amc
Synonym More Synonyms

 Ac-Trp-Glu-His-Asp-AMC Biological Activity

Description Ac-Trp-Glu-His-Asp-AMC (Ac-Trp-Glu-His-Asp-AMC) is a potent fluorogenic substrate of caspase-1[1].
Related Catalog
References

[1]. Kindermann M, et al. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol. 2010 Sep 24;17(9):999-1007.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1399.8±65.0 °C at 760 mmHg
Molecular Formula C38H40N8O11
Molecular Weight 784.771
Flash Point 800.3±34.3 °C
Exact Mass 784.281677
PSA 294.78000
LogP 1.29
Appearance of Characters powder | white
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.667
Storage condition −20°C

 Safety Information

WGK Germany 3

 Synonyms

ac-trp-glu-his-asp-mca
ac-trp-glu-his-asp-7-amino-4-methylcoumarin
L-α-Asparagine, N-acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
pase-5 substrate iii,fluorogenic
ac-trp-glu-his-asp-amc
ac-wehd-mca
n-acetyl-trp-glu-his-asp 7-amido-4-methylcoumarin
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine
pase-1 substrate x,fluorogenic