1-Deoxynojirimycin

Modify Date: 2024-01-01 17:33:18

1-Deoxynojirimycin Structure
1-Deoxynojirimycin structure
 Common Name 1-Deoxynojirimycin
CAS Number 19130-96-2 Molecular Weight 163.172
Density 1.5±0.1 g/cm3 Boiling Point 361.1±42.0 °C at 760 mmHg
Molecular Formula C6H13NO4 Melting Point 195-196°C
MSDS N/A Flash Point 197.3±18.5 °C

 Use of 1-Deoxynojirimycin


1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillusspecies.

 Names

Name duvoglustat
Synonym More Synonyms

 1-Deoxynojirimycin Biological Activity

Description 1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillusspecies.
Related Catalog
References

[1]. Chaluntorn Vichasilp,et al. Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction. LWT - Food Science and Technology. Volume 45, Issue 2, Marc

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 361.1±42.0 °C at 760 mmHg
Melting Point 195-196°C
Molecular Formula C6H13NO4
Molecular Weight 163.172
Flash Point 197.3±18.5 °C
Exact Mass 163.084457
PSA 92.95000
LogP -2.10
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.582
Storage condition Desiccate at +4°C

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S37/39-S24/25
WGK Germany 3
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(2R,3R,4R,5S)-2-Hydroxymethyl-3,4,5-trihydroxypiperidine
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R,3R,4R,5S)-
D-5-Amino-1,5-dideoxyglucopyranose
deoxynojirimycin
MFCD00063474
MORANOLINE
(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol
Duvoglustat
(2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol
1,5-Dideoxy-1,5-imino-D-glucitol
(+)-1-deoxynojirimycin
1-Deoxy-Nojirimycin
desoxynojirimycin
(2R,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol
S-GI
[2R-(2a,3b,4a,5b)]-2-(Hydroxymethyl)-3,4,5-piperidinetriol
nojirimycin, deoxy-
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