Prosaptide Tx14(A) TFA

Modify Date: 2024-01-05 17:09:49

Prosaptide Tx14(A) TFA structure	Common Name	Prosaptide Tx14(A) TFA
	CAS Number	196391-82-9	Molecular Weight	1579.70
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₉H₁₁₀N₁₆O₂₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Prosaptide Tx14(A) TFA

Prosaptide Tx14(A), a prosaposin-derived peptide, is a potent GPR37L1 and GPR37 agonist with EC50s of 5 and 7 nM, respectively. Prosaptide Tx14(A) increases both ERK1 and ERK2 phosphorylation in Schwann cells[1][2].

Name	Prosaptide Tx14(A)

Description	Prosaptide Tx14(A), a prosaposin-derived peptide, is a potent GPR37L1 and GPR37 agonist with EC50s of 5 and 7 nM, respectively. Prosaptide Tx14(A) increases both ERK1 and ERK2 phosphorylation in Schwann cells[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	Prosaptide Tx14(A) promotes the endocytosis of GPR37 and GPR37L1, bound to both receptors and activated signaling in a GPR37- and GPR37L1-dependent manner. Prosaptide Tx14(A) is the active fragment of the secreted neuroprotective and glioprotective factor prosaposin (also known as sulfated glycoprotein-1)[1].
References	[1]. Meyer RC, et al. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. Proc Natl Acad Sci U S A. 2013;110(23):9529-9534. [2]. Campana WM, et al. Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells. FASEB J. 1998;12(3):307-314.

Molecular Formula	C₆₉H₁₁₀N₁₆O₂₆
Molecular Weight	1579.70

DC Chemicals Limited
China
Product Name: Prosaptide Tx14(A) TFA
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Taiwan Oyi peptide Co. Ltd
China
Product Name: Prosaptide Tx14(A) TFA
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

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