T 98475

Modify Date: 2024-01-18 10:49:50

T 98475 structure	Common Name	T 98475
	CAS Number	199119-18-1	Molecular Weight	657.77
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₇H₃₇F₂N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of T 98475

T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.2 nM[1].

Name	Isopropyl 3-{[benzyl(methyl)amino]methyl}-7-(2,6-difluorobenzyl)- 2-[4-(isobutyrylamino)phenyl]-4-oxo-4,7-dihydrothieno[2,3-b]pyrid ine-5-carboxylate

Description	T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.2 nM[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Others
Target	IC50: 0.2 nM (human LHRH receptor), 2 nM (monkey LHRH receptor), 4 nM (monkey anterior pituitaries), 60 nM (rat anterior pituitaries)[1]
References	[1]. Imada T, et al. Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists. J Med Chem. 2006 Jun 29;49(13):3809-25.

Molecular Formula	C₃₇H₃₇F₂N₃O₄S
Molecular Weight	657.77
Exact Mass	657.24700
PSA	108.88000
LogP	7.92120

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: T 98475
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Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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