Xanthotoxol

Modify Date: 2024-01-03 19:43:07

Xanthotoxol Structure
Xanthotoxol structure
Common Name Xanthotoxol
CAS Number 2009-24-7 Molecular Weight 202.163
Density 1.5±0.1 g/cm3 Boiling Point 428.1±45.0 °C at 760 mmHg
Molecular Formula C11H6O4 Melting Point 250ºC
MSDS N/A Flash Point 212.7±28.7 °C

 Use of Xanthotoxol


Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.

 Names

Name Xanthotoxol
Synonym More Synonyms

 Xanthotoxol Biological Activity

Description Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
Related Catalog
Target

5-HT[1]

References

[1]. Ma Z, et al. Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes. Evid Based Complement Alternat Med. 2016;2016:5416509.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 428.1±45.0 °C at 760 mmHg
Melting Point 250ºC
Molecular Formula C11H6O4
Molecular Weight 202.163
Flash Point 212.7±28.7 °C
Exact Mass 202.026611
PSA 63.58000
LogP 0.72
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.711
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV1069000
CHEMICAL NAME :
7H-Furo(3,2-g)(1)benzopyran-7-one, 9-hydroxy-
CAS REGISTRY NUMBER :
2009-24-7
BEILSTEIN REFERENCE NO. :
0189491
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H6-O4
MOLECULAR WEIGHT :
202.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 36,239,1992
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 36,239,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
468 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 36,239,1992

 Safety Information

Risk Phrases 25
Safety Phrases 20-45
RIDADR UN 2810
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

9-hydroxyfuro[3,2-g]chromen-7-one
8-Hydroxypsoralen
T C566 DO LVOJ BQ
8-Hydroxy-4':5',6:7-furocoumarin
7H-Furo[3,2-g][1]benzopyran-7-one, 9-hydroxy-
9-Hydroxy-7H-furo[3,2-g]chromen-7-one
Xanthotoxol
EINECS 217-923-1
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