HEPES-d18
Modify Date: 2024-01-21 16:32:59
HEPES-d18 structure
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Common Name | HEPES-d18 | ||
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| CAS Number | 203805-87-2 | Molecular Weight | 256.415 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C8D18N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HEPES-d18HEPES-d18 is the deuterium labeled HEPES[1]. HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis[2][3][4]. |
| Name | hepes (d18) |
|---|---|
| Synonym | More Synonyms |
| Description | HEPES-d18 is the deuterium labeled HEPES[1]. HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis[2][3][4]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
[3]. Sledź P, et al. An experimental charge density of HEPES. Acta Crystallogr B. 201066(Pt 4):482-492. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C8D18N2O4S |
| Molecular Weight | 256.415 |
| Exact Mass | 256.211700 |
| PSA | 89.46000 |
| LogP | -2.67 |
| Index of Refraction | 1.543 |
| Piperazine-2,2,3,3,5,5,6,6-d-1-ethane-α,α,β,β-d-sulfonic acid-d, 4-[2-(hydroxy-d)ethyl-1,1,2,2-d]- |
| 2-{4-[2-(H)Hydroxy(H)ethyl](H)-1-piperazinyl}(H)ethane(H)sulfonic acid |
| 2-{4-[2-(H)Hydroxy(H)ethyl](H)piperazin-1-yl}(H)ethane(H)sulfonic acid |