IWP-O1 structure
|
Common Name | IWP-O1 | ||
---|---|---|---|---|
CAS Number | 2074607-48-8 | Molecular Weight | 432.48 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C26H20N6O | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of IWP-O1IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells, suppressing the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. IWP-O1 functions by preventing the secretion of Wnt proteins[1]. |
Name | IWP-O1 |
---|
Description | IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells, suppressing the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. IWP-O1 functions by preventing the secretion of Wnt proteins[1]. |
---|---|
Related Catalog | |
Target |
EC50: 80 pM (Porcn)[1]. |
References |
Molecular Formula | C26H20N6O |
---|---|
Molecular Weight | 432.48 |
Storage condition | -20℃ |