sAJM-589

Modify Date: 2024-02-03 12:07:31

sAJM-589 Structure
sAJM-589 structure
Common Name sAJM-589
CAS Number 2089-82-9 Molecular Weight 246.26300
Density N/A Boiling Point N/A
Molecular Formula C16H10N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of sAJM-589


sAJM-589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].

 Names

Name 6H-benzo[a]phenazin-5-ol
Synonym More Synonyms

 sAJM-589 Biological Activity

Description sAJM-589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].
Related Catalog
Target

IC50: 1.8 μM (Myc)[1]

In Vitro sAJM-589 potently disrupts the Myc-Max heterodimer in a dose dependent manner with an IC50of 1.8 μM[1]. sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1].
References

[1]. Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.

 Chemical & Physical Properties

Molecular Formula C16H10N2O
Molecular Weight 246.26300
Exact Mass 246.07900
PSA 46.01000
LogP 3.64180

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Hydroxy-1,2-benzophenazin
Top Suppliers:I want be here



Get all suppliers and price by the below link:

sAJM-589 suppliers

sAJM-589 price