2089-82-9
2089-82-9 structure
- Name: sAJM-589
- Chemical Name: 6H-benzo[a]phenazin-5-ol
- CAS Number: 2089-82-9
- Molecular Formula: C16H10N2O
- Molecular Weight: 246.26300
- Catalog: Signaling Pathways Apoptosis c-Myc
- Create Date: 2016-08-13 16:58:41
- Modify Date: 2024-02-03 12:07:31
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sAJM-589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].
| Name | 6H-benzo[a]phenazin-5-ol |
|---|---|
| Synonyms | 3-Hydroxy-1,2-benzophenazin |
| Description | sAJM-589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.8 μM (Myc)[1] |
| In Vitro | sAJM-589 potently disrupts the Myc-Max heterodimer in a dose dependent manner with an IC50of 1.8 μM[1]. sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1]. |
| References |
| Molecular Formula | C16H10N2O |
|---|---|
| Molecular Weight | 246.26300 |
| Exact Mass | 246.07900 |
| PSA | 46.01000 |
| LogP | 3.64180 |
| HS Code | 2933990090 |
|---|
| Precursor 0 | |
|---|---|
| DownStream 4 | |
![Benzo[a]phenazine structure](https://image.chemsrc.com/caspic/324/225-61-6.png)
![2-N-benzo[a]phenazin-5-ylbenzene-1,2-diamine structure](https://image.chemsrc.com/caspic/489/61316-12-9.png)
![5-(2-methylbenzimidazol-1-yl)benzo[a]phenazine structure](https://image.chemsrc.com/caspic/289/61316-17-4.png)
![N-[2-(benzo[a]phenazin-5-ylamino)phenyl]acetamide structure](https://image.chemsrc.com/caspic/282/61316-66-3.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |