FASN-IN-3
Modify Date: 2024-01-08 10:52:56
FASN-IN-3 structure
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Common Name | FASN-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2097262-60-5 | Molecular Weight | 384.4798 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FASN-IN-3FASN inhibitor 1 is a fatty acid synthase (FASN) inhibitor extracted from patent US20170119786A1, compound 242A. |
| Name | FASN inhibitor 1 |
|---|
| Description | FASN inhibitor 1 is a fatty acid synthase (FASN) inhibitor extracted from patent US20170119786A1, compound 242A. |
|---|---|
| Related Catalog | |
| Target |
FASN[1] |
| In Vitro | Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN inhibitor 1 (Compound 242A), results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation. For monocytes, FASN inhibitor 1 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation[1]. |
| References |
[1]. Buckley, Douglas I, et al. HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS. US20170119786A1 |
| Molecular Formula | C24H24N4O |
|---|---|
| Molecular Weight | 384.4798 |