PROTAC BRD4-binding moiety 1

Modify Date: 2024-01-12 04:13:30

PROTAC BRD4-binding moiety 1 structure	Common Name	PROTAC BRD4-binding moiety 1
	CAS Number	2101200-10-4	Molecular Weight	371.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC BRD4-binding moiety 1

PROTAC BRD4-binding moiety 1 is a ligand for BRD4. PROTAC BRD4-binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY-133136)[1].

Name	PROTAC BRD4-binding moiety 1

Description	PROTAC BRD4-binding moiety 1 is a ligand for BRD4. PROTAC BRD4-binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY-133136)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4
In Vitro	PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1].
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₂₃H₂₁N₃O₂
Molecular Weight	371.43
Storage condition	2-8°C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PROTAC BRD4-binding moiety 1
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Purity: 98.0%
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