Propargyl-PEG10-amine

Modify Date: 2024-01-07 15:24:28

Propargyl-PEG10-amine Structure
Propargyl-PEG10-amine structure
Common Name Propargyl-PEG10-amine
CAS Number 2112737-25-2 Molecular Weight 495.60
Density N/A Boiling Point N/A
Molecular Formula C23H45NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG10-amine


Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name Propargyl-PEG10-amine

 Propargyl-PEG10-amine Biological Activity

Description Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.

 Chemical & Physical Properties

Molecular Formula C23H45NO10
Molecular Weight 495.60
Storage condition 2-8°C