Propargyl-PEG10-alcohol

Modify Date: 2024-01-10 21:04:01

Propargyl-PEG10-alcohol Structure
Propargyl-PEG10-alcohol structure
Common Name Propargyl-PEG10-alcohol
CAS Number 2378150-09-3 Molecular Weight 496.59
Density N/A Boiling Point N/A
Molecular Formula C23H44O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG10-alcohol


Propargyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG10-alcohol

 Propargyl-PEG10-alcohol Biological Activity

Description Propargyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H44O11
Molecular Weight 496.59
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