877239-09-3

877239-09-3 structure

Name: Azido-PEG10-alcohol
Chemical Name: Azido-PEG10-alcohol
CAS Number: 877239-09-3
Molecular Formula: C₂₀H₄₁N₃O₁₀
Molecular Weight: 483.55
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-21 08:42:49
Modify Date: 2024-01-09 23:13:37
Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG10-alcohol

Description	Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562