Mal-NH-PEG12-CH2CH2COOPFP ester

Modify Date: 2024-01-13 15:59:41

Mal-NH-PEG12-CH2CH2COOPFP ester structure	Common Name	Mal-NH-PEG12-CH2CH2COOPFP ester
	CAS Number	2136296-33-6	Molecular Weight	934.89
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₀H₅₉F₅N₂O₁₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mal-NH-PEG12-CH2CH2COOPFP ester

Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-NH-PEG12-CH2CH2COOPFP ester

Description	Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₄₀H₅₉F₅N₂O₁₇
Molecular Weight	934.89

Hazard Codes	Xi