Pomalidomide 4'-PEG5-acid structure
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Common Name | Pomalidomide 4'-PEG5-acid | ||
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CAS Number | 2139348-63-1 | Molecular Weight | 565.57 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C26H35N3O11 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Pomalidomide 4'-PEG5-acidPomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1]. |
Name | Pomalidomide 4'-PEG5-acid |
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Description | Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1]. |
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Related Catalog | |
Target |
Cereblon |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C26H35N3O11 |
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Molecular Weight | 565.57 |
Storage condition | -20°C |