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882847-32-7

882847-32-7 structure
882847-32-7 structure
  • Name: Fmoc-amino-PEG5-acid
  • Chemical Name: 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azadocosan-22-oic acid
  • CAS Number: 882847-32-7
  • Molecular Formula: C28H37NO9
  • Molecular Weight: 531.59500
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-22 21:29:24
  • Modify Date: 2024-01-07 11:19:24
  • Fmoc-amino-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azadocosan-22-oic acid
Synonyms fmoc-18-amino-4,7,10,13,16-pentaoxaoctadecanoic acid
5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
Description Fmoc-amino-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.210±0.06 g/cm3 (20ºC 760 Torr)
Boiling Point 711.4±60.0°C at 760 mmHg
Molecular Formula C28H37NO9
Molecular Weight 531.59500
Exact Mass 531.24700
PSA 121.78000
LogP 3.47370
HS Code 29225090