Thalidomide-NH-PEG1-NH2 hydrochloride
Modify Date: 2024-08-08 17:54:59
Thalidomide-NH-PEG1-NH2 hydrochloride structure
|
Common Name | Thalidomide-NH-PEG1-NH2 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2154342-56-8 | Molecular Weight | 396.83 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H21ClN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-PEG1-NH2 hydrochlorideThalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-NH-PEG1-NH2 hydrochloride |
|---|
| Description | Thalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C17H21ClN4O5 |
|---|---|
| Molecular Weight | 396.83 |
| Hazard Codes | Xi |
|---|