Thalidomide-NH-PEG1-C2-NH2
Modify Date: 2024-01-14 10:26:05
Thalidomide-NH-PEG1-C2-NH2 structure
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Common Name | Thalidomide-NH-PEG1-C2-NH2 | ||
|---|---|---|---|---|
| CAS Number | 2138439-12-8 | Molecular Weight | 360.365 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 660.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C17H20N4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 353.3±31.5 °C | |
Use of Thalidomide-NH-PEG1-C2-NH2Thalidomide-NH-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | 4-{[2-(2-Aminoethoxy)ethyl]amino}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Thalidomide-NH-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 660.5±55.0 °C at 760 mmHg |
| Molecular Formula | C17H20N4O5 |
| Molecular Weight | 360.365 |
| Flash Point | 353.3±31.5 °C |
| Exact Mass | 360.143372 |
| LogP | -1.06 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.647 |
| Hazard Codes | Xi |
|---|
| 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)- |
| 4-{[2-(2-Aminoethoxy)ethyl]amino}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Thalidomide-NH-PEG1-C2-NH2
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Thalidomide-NH-PEG1-C2-NH2
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Thalidomide-NH-PEG1-C2-NH2
- Price: $500.0/100mg $900.0/250mg $1700.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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