Glucocorticoid receptor agonist-2

Modify Date: 2024-04-09 19:09:38

Glucocorticoid receptor agonist-2 Structure
Glucocorticoid receptor agonist-2 structure
Common Name Glucocorticoid receptor agonist-2
CAS Number 2166378-92-1 Molecular Weight 607.64
Density N/A Boiling Point N/A
Molecular Formula C34H35F2NO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Glucocorticoid receptor agonist-2


Glucocorticoid receptor agonist-2 (compound 21) is an Glucocorticoid Receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373[1].

 Names

Name Glucocorticoid receptor agonist-2

 Glucocorticoid receptor agonist-2 Biological Activity

Description Glucocorticoid receptor agonist-2 (compound 21) is an Glucocorticoid Receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373[1].
Related Catalog
In Vitro Glucocorticoid receptor agonist-2 对糖皮质激素受体 (GR) 和孕激素受体 (PR) 结合的 IC50 值分别为 6.6 和 7.3 nM[1]。 Glucocorticoid receptor agonist-2 对糖皮质激素效应元件 (GRE) 报告基因和盐皮质激素受体 (MR) 的 EC50 值分别为 0.2 和 442 nM[1]。 Glucocorticoid receptor agonist-2 对盐皮质激素受体激动活性的 EC50 值为 149 nM[1]。
References

[1]. Mcpherson MJ, et al. Preparation of glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471. 2017.

 Chemical & Physical Properties

Molecular Formula C34H35F2NO7
Molecular Weight 607.64
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