GW 275175X structure
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Common Name | GW 275175X | ||
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CAS Number | 217950-62-4 | Molecular Weight | 398.034 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C12H11BrCl2N2O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of GW 275175XGW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion. |
Name | GW 275175X |
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Description | GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion. |
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References | References 1. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92. 2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51. View Related Products by Target CMV |
Molecular Formula | C12H11BrCl2N2O4 |
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Molecular Weight | 398.034 |