GW 275175X

Modify Date: 2024-07-22 14:11:41

GW 275175X Structure
GW 275175X structure
Common Name GW 275175X
CAS Number 217950-62-4 Molecular Weight 398.034
Density N/A Boiling Point N/A
Molecular Formula C12H11BrCl2N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GW 275175X


GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion.

 Names

Name GW 275175X

 GW 275175X Biological Activity

Description GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion.
References References 1. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92. 2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51. View Related Products by Target CMV

 Chemical & Physical Properties

Molecular Formula C12H11BrCl2N2O4
Molecular Weight 398.034
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