Ac-Val-Glu-Ile-Asp-AMC

Modify Date: 2024-01-08 16:24:52

Ac-Val-Glu-Ile-Asp-AMC Structure
Ac-Val-Glu-Ile-Asp-AMC structure
Common Name Ac-Val-Glu-Ile-Asp-AMC
CAS Number 219137-97-0 Molecular Weight 673.711
Density 1.3±0.1 g/cm3 Boiling Point 1106.8±65.0 °C at 760 mmHg
Molecular Formula C32H43N5O11 Melting Point N/A
MSDS N/A Flash Point 623.2±34.3 °C

 Use of Ac-Val-Glu-Ile-Asp-AMC


Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm)[1].

 Names

Name ac-veid-amc
Synonym More Synonyms

 Ac-Val-Glu-Ile-Asp-AMC Biological Activity

Description Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm)[1].
Related Catalog
In Vitro Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). Enzyme activity (rabbit osteoclasts for example)[1]: 1. Treat purified, differentiated cells by medium for 48 h (time depends on the cell). 2. Put treated cells into 4.5 mL lysis buffer. 3. Each lysate is divided into thirds, then incubate with 40 µM Ac-VEID-AMC at 37°C for 1 h. 4. Detect cleavage of fluorescent substrates (Ex=340-360 nm, Em=440-460 nm)

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1106.8±65.0 °C at 760 mmHg
Molecular Formula C32H43N5O11
Molecular Weight 673.711
Flash Point 623.2±34.3 °C
Exact Mass 673.295898
PSA 250.31000
LogP 2.36
Appearance of Characters powder | white
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.571
Storage condition −20°C

 Synonyms

L-α-Asparagine, N-acetyl-L-valyl-L-α-glutamyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
Ac-Val-Glu-IIe-Asp-7-amino-4-methylcoumarin
N-Acetyl-L-valyl-L-α-glutamyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine
AC-VAL-GLU-ILE-ASP-MCA
AC-VEID-MCA
PASE-6 SUBSTRATE I,FLUOROGENIC
AC-VAL-GLU-ILE-ASP-AMC
N-ACETYL-VAL-GLU-ILE-ASP-7-AMINO-4-METHYLCOUMARIN AMC
AC-VAL-GLU-ILE-ASP-7-AMINO-4-METHYLCOUMARIN
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