TH-Z93

Modify Date: 2024-07-21 12:17:02

TH-Z93 Structure
TH-Z93 structure
Common Name TH-Z93
CAS Number 2260887-09-8 Molecular Weight 368.26
Density N/A Boiling Point N/A
Molecular Formula C12H22N2O7P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TH-Z93


TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM)[1].

 Names

Name TH-Z93

 TH-Z93 Biological Activity

Description TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM)[1].
Related Catalog
Target

FPPS[1]

In Vivo TH-Z93 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model[1]. Animal Model: B16-OVA cells (s.c.) xenograft mice model[1]. Dosage: 20 μg Administration: Intraperitoneal injection (i.p.) Result: Intraperitoneal injection (i.p.)
References

[1]. Xia Y, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018 Nov 1;175(4):1059-1073.e21.

 Chemical & Physical Properties

Molecular Formula C12H22N2O7P2
Molecular Weight 368.26